METEOR

Increase the cryo-ET sample yield by eliminating complicated transfer steps

Introduction

The current cryo-CLEM workflow is laborious, requires expert users and has a low yield. Integrating a fluorescence light microscope (FLM) into a FIB/SEM system directly reduces the complexity of the workflow. This decreases the chance to damage, contaminate or devitrify your sample and increases the efficiency of the workflow.

METEOR removes the need for transporting your samples for cryo-CLEM between platforms by integrating a FLM with your cryo-FIB/SEM. It is easily retrofittable and adaptable to your existing workflow and cryo-stage. 

Benefits

Integration minimizes transfer steps

By integrating an FLM into your FIB/SEM many transfer steps are removed, reducing the risk of damage, devitrification or contamination of your sample.

Increase yield

Currently, the yield of the cryo-CLEM workflow is as low as 20%, METEOR will increase the yield by minimizing complicated transfer steps.

Increase throughput of samples

By simplifying the workflow METEOR will increase the throughput of the sample preparation for cryo-ET and ultimately allows for a higher efficiency in the analysis of biological structures to be achieved.

Less sample damage

Less sample damage translates into less cryo-TEM time being spent on substandard samples, resulting in a lower cost per sample analysed.

Reduce costs

Reduces purchase and maintenance costs by abolishing the need for a separate cryo-FLM system.